AllTrials is a project advocating that clinical research adopt the principles of open research. The project summarizes itself as “All trials registered, all results reported”: that is, all clinical trials should be listed in a clinical trials registry, and their results should always be shared as open data.
A substantial proportion (estimates range from one-third to one-half) of medical research goes unpublished. It has also been shown that negative findings are less likely to be published than positive ones, even in the absence of conflicts of interest.
Much medical research is done by the pharmaceutical industry, which have a conflict of interest reporting results which may hurt sales of their products.